The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Sep. 11, 2019
Applicants:
The University of Chicago, Chicago, IL (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Inventors:
Hans Schreiber, Chicago, IL (US);
David Kranz, Champaign, IL (US);
Karin Schreiber, Chicago, IL (US);
Yanran He, Chicago, IL (US);
Preeti Sharma, Urbana, IL (US);
Assignees:
The University of Chicago, Chicago, IL (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/70 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C07K 14/725 (2006.01); C07K 14/735 (2006.01); C07K 16/18 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4259 (2025.01); A61P 35/00 (2018.01); C07K 14/70535 (2013.01); C07K 16/18 (2013.01); C12N 5/0638 (2013.01); A61K 2239/13 (2023.05); A61K 2239/31 (2023.05); A61K 2239/38 (2023.05); A61K 2239/48 (2023.05); A61K 2239/59 (2023.05);
Abstract
The disclosure provides Tn epitope-specific chimeric antigen receptors and scFvs, including soluble scFvs and multimeric scFvs, as well as methods of identifying cancer subjects and cancer subject sub-populations amenable to anti-Tn immunotherapy and methods of treating cancer.