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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12398172 B1

PDFFull Text
Date of Patent:
Aug. 26, 2025

Filed:

Jun. 30, 2023

Therapeutic oligonucleotides

Applicant:

Caris Science, Inc., Irving, TX (US);

Inventors:

Heather O'neill, Mesa, AZ (US);

Günter Mayer, Bonn, DE;

Mark Miglarese, Phoenix, AZ (US);

David Spetzler, Paradise Valley, AZ (US);

Assignee:

Caris Science, Inc., Irving, TX (US);

Attorney:

Kilpatrick Townsend & Stockton LLP

Primary Examiner:

Ekaterina Poliakova-Georgantas

Int. Cl.
CPC ...
C12N 15/115 (2010.01); A61K 9/00 (2006.01); A61K 47/69 (2017.01); A61P 9/00 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); C07H 19/09 (2006.01); C07H 19/173 (2006.01); C07H 19/19 (2006.01); C07H 21/00 (2006.01); C12N 15/10 (2006.01); C12Q 1/6886 (2018.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
C07H 19/173 (2013.01); A61K 9/0014 (2013.01); A61K 9/0019 (2013.01); A61K 9/0053 (2013.01); A61K 47/6911 (2017.08); A61K 47/6929 (2017.08); A61P 9/00 (2018.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); A61P 31/00 (2018.01); A61P 35/02 (2018.01); A61P 37/00 (2018.01); C07H 19/09 (2013.01); C07H 19/19 (2013.01); C07H 21/00 (2013.01); C12N 15/10 (2013.01); C12N 15/115 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5308 (2013.01); G01N 33/57484 (2013.01); G01N 33/68 (2013.01); G06T 7/0012 (2013.01); C12N 2310/16 (2013.01); C12N 2320/10 (2013.01); C12Q 2600/158 (2013.01);
Abstract

Methods and compositions are provided for oligonucleotides that bind targets of interest. The targets include cells and microvesicles, such as those derived from various diseases. The oligonucleotides can be used for diagnostic and therapeutic purposes. The target of the oligonucleotides can be a target such as PARP1, HIST1H1B, HIST1H1D, NCL, FBL, SFPQ, RPL12, ACTB, HIST1H4A, SSBP1, NONO, H2AFJ, and DDX21, or a complex, subunit or fragment thereof.

Find Patent Forward Citations

O'neill, Heather. (2025). Therapeutic oligonucleotides (U.S. Patent No. 12398172). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12398172

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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