The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Jan. 31, 2020
Applicant:
Osaka University, Osaka, JP;
Inventors:
Satoshi Obika, Osaka, JP;
Takao Yamaguchi, Osaka, JP;
Takaki Habuchi, Osaka, JP;
Go Kato, Osaka, JP;
Takao Inoue, Osaka, JP;
Tokuyuki Yoshida, Osaka, JP;
Takaya Sugiura, Osaka, JP;
Assignee:
Osaka University, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/10 (2006.01); C07H 19/20 (2006.01); C07H 21/00 (2006.01);
U.S. Cl.
CPC ...
C07H 19/10 (2013.01); C07H 19/20 (2013.01); C07H 21/00 (2013.01);
Abstract
Disclosed are a 5′-modified nucleoside and a nucleotide using the same. The nucleoside of the present invention is represented by the formula (I) below. The 5′-modified nucleoside of the present invention is usable as a substitute for a phosphorothioate-modified nucleic acid, which has a risk of, for example, accumulation in a specific organ. The 5′-modified nucleoside also has excellent industrial productivity because a diastereomer separation step is not involved in the production process thereof.