The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Mar. 05, 2020
Applicants:
Centre for Addiction and Mental Health, Toronto, CA;
The University Court of the University of Aberdeen, Aberdeen, GB;
Inventors:
Fang Liu, Toronto, CA;
Iain Greig, Aberdeen, GB;
Dongxu Zhai, Toronto, CA;
Stephen Allan Smith, London, GB;
Chiara Zanato, Aberdeen, GB;
Chih-Chung Tseng, Aberdeen, GB;
Assignees:
Centre for Addiction and Mental Health, Toronto, CA;
The University Court of the University of Aberdeen, Aberdeen, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 25/00 (2018.01);
Abstract
Provided are compounds of Formula (I) which have shown utility in modulating AMPA receptor signaling and thus preventing AMPA receptor-mediated toxicity, which may find use in the treatment of diseases in which AMPA receptor activation plays a role in neurodegeneration, including the treatment of multiple sclerosis and other diseases.