The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Jul. 28, 2023
Applicant:

Sumitomo Pharma Co., Ltd., Osaka, JP;

Inventors:

Hitoshi Watanabe, Osaka, JP;

Shuya Yamada, Osaka, JP;

Katsushi Kitahara, Osaka, JP;

Mariko Kobayashi, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/497 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/553 (2006.01); A61P 25/16 (2006.01); C07D 401/14 (2006.01); C07D 413/14 (2006.01); C07D 491/04 (2006.01); C07D 491/08 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/497 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/553 (2013.01); A61P 25/16 (2018.01); C07D 401/14 (2013.01); C07D 413/14 (2013.01); C07D 491/04 (2013.01); C07D 491/08 (2013.01);
Abstract

The present invention relates to a medicament for treating or preventing central nervous system disease whose cause is related to abnormal aggregation of proteins in the brain, which comprises as an active ingredient a compound of formula (1) or a pharmaceutically acceptable salt thereof, wherein Rand Rare hydrogen, etc., Rand Rare hydrogen, Calkyl, etc., Ris halogen, Calkyl, etc., Ris hydrogen, halogen, etc., X is oxygen, etc., Y is carbon, etc., m and n are an integer of 0, 1, etc., r and s are 0, 1, 2, etc., Hy is pyridine ring, etc., which has an action of suppressing or reducing the accumulation of abnormal aggregation of proteins in the brain.


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