The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Feb. 24, 2023
Legochem Biosciences, Inc., Daejeon, KR;
Ho Young Song, Daejeon, KR;
Sung Min Kim, Daejeon, KR;
Hyoungrae Kim, Daejeon, KR;
Kyung Eun Park, Daejeon, KR;
Chul-Woong Chung, Daejeon, KR;
Yun-Hee Park, Daejeon, KR;
Hyo Jung Choi, Daejeon, KR;
Su In Lee, Daejeon, KR;
Juyuel Baek, Daejeon, KR;
Hyeun Joung Lee, Daejeon, KR;
Ju Young Lee, Daejeon, KR;
Ji Hye Oh, Daejeon, KR;
Jeiwook Chae, Daejeon, KR;
Yeong Soo Oh, Daejeon, KR;
Yong Zu Kim, Daejeon, KR;
LigaChem Biosciences Inc., Daejeon, KR;
Abstract
The present invention relates to a pyrrolobenzodiazepine dimer prodrug and a ligand-linker conjugate compound thereof, a composition containing these, and therapeutic use thereof particularly as an anticancer drug. The stability of the compounds themselves and the stability thereof in plasma are excellent and the compounds are advantageous in terms of manifestation of toxicity, and thus the compounds are industrially useful in that it is possible to target proliferative diseases such as cancer, to perform a specific treatment, to maximize the drug efficacy, and to minimize the occurrence of side effects.