The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Mar. 19, 2020
Applicant:

Piramal Pharma Limited, Mumbai, IN;

Inventors:

Venkataramana Rao Rao, Telegana, IN;

Sharadsrikar Kotturi, Gujarat, IN;

Abdul Basith, Telegana, IN;

Ramesh Babu Bandi, Telegana, IN;

Manoj Kumar Mandadi, Telegana, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 319/18 (2006.01); C07F 1/08 (2006.01); C07F 3/06 (2006.01); C07F 15/04 (2006.01);
U.S. Cl.
CPC ...
C07D 319/18 (2013.01); C07F 1/08 (2013.01); C07F 3/06 (2013.01); C07F 15/045 (2013.01);
Abstract

The present invention relates to an improved process for the preparation of N-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide (A), which is known as ELIGLUSTAT and its pharmaceutically acceptable salts, comprising the formation of novel intermediate metal complex (III), which on hydrolysis in presence of acid provides amine compound (IV) (as described herein), which is treated with pyrrolidine and subsequently reduced to convert into Eliglustat (A).


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Rao, Venkataramana. (2025). Process for the preparation of eliglustat and its intermediate (U.S. Patent No. 12398114). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12398114

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