The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Jul. 14, 2023
Applicant:
Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;
Inventors:
Yoram Cohen, Tel Aviv, IL;
Micha Fridman, Tel Aviv, IL;
Roymon Joseph, Tel Aviv, IL;
Alissa Naugolny, Tel Aviv, IL;
Mark Feldman, Tel Aviv, IL;
Ido M. Herzog, Tel Aviv, IL;
Dana Kaizerman, Tel Aviv, IL;
Assignee:
Ramot at Tel-Aviv University Ltd., Tel Aviv, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/138 (2006.01); A61K 31/4178 (2006.01); A61K 31/66 (2006.01); A61K 45/06 (2006.01); C02F 1/50 (2023.01); C07C 217/54 (2006.01); C07D 233/60 (2006.01); C07F 9/54 (2006.01); C09D 5/16 (2006.01);
U.S. Cl.
CPC ...
C07C 217/54 (2013.01); A61K 31/138 (2013.01); A61K 31/4178 (2013.01); A61K 31/66 (2013.01); A61K 45/06 (2013.01); C02F 1/50 (2013.01); C07D 233/60 (2013.01); C07F 9/5407 (2013.01); C09D 5/1687 (2013.01); C02F 2303/20 (2013.01);
Abstract
Cationic pillar[n]arenes, e.g., positively charged poly-ammonium, poly-phosphonium and poly-imidazolium pillar[5-6]arene derivatives are capable of inhibiting or preventing biofilm formation, and facilitating existing biofilm decomposition. A composition for inhibiting or disrupting biofilm, e.g., bacterial or fungal biofilm, formation, or reducing biofilm, can include a pharmaceutically acceptable carrier, and a cationic pillar[n]ene.