The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Jan. 13, 2021
Know Bio, Llc, Durham, NC (US);
Nathan Stasko, Chapel Hill, NC (US);
David T. Emerson, Durham, NC (US);
Adam Cockrell, Durham, NC (US);
F. Neal Hunter, Durham, NC (US);
Michael John Bergmann, Atlanta, GA (US);
Rebecca Mcdonald, Chapel Hill, NC (US);
Nicholas William Medendorp, Jr., Raleigh, NC (US);
Gerald H. Negley, Chapel Hill, NC (US);
Katelyn P. Reighard, Durham, NC (US);
KNOW BIO, LLC, Morrisville, NC (US);
Abstract
Methods and related devices for impinging light on tissue, for example within a body of a patient, to induce various biological effects are disclosed. Biological effects may include at least one of inactivating and/or inhibiting growth of one or more pathogens, upregulating a local immune response, stimulating enzymatic generation of nitric oxide to increase endogenous stores of nitric oxide, releasing nitric oxide from endogenous stores of nitric oxide, and inducing an anti-inflammatory effect. Wavelengths of light are selected based on intended biological effects for one or more of targeted tissue types and targeted pathogens. Light treatments may provide multiple pathogenic biological effects, either with light of a single wavelength or with light having multiple wavelengths. Devices and methods for light treatments are disclosed that provide light doses for inducing biological effects on various targeted pathogens and targeted tissues with increased efficacy and reduced cytotoxicity.