The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Apr. 27, 2021
Applicant:

Florida Southern College, Lakeland, FL (US);

Inventors:

Shameka J. Shelby, Auburndale, FL (US);

Zachary D. Fralish, Niceville, FL (US);

Keith R. Berend, New Albany, OH (US);

Assignee:

Florida Southern College, Lakeland, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 26/00 (2006.01);
U.S. Cl.
CPC ...
A61L 26/0066 (2013.01); A61L 26/0038 (2013.01); A61L 2300/406 (2013.01); A61L 2300/602 (2013.01); A61L 2400/04 (2013.01);
Abstract

A novel active agent-eluting hemostatic agent and methods of use and manufacture thereof are presented. A polymer, such as gelatin, is used as the base for a hemostatic agent. The gelatin is crosslinked with a chemical crosslinker, such as a carbodiimide, in the presence of an active agent. The active agent may be an anesthetic or antimicrobial, such as an antibiotic. The novel process allows for the active agent to be both covalently bound to the gelatin as well as be trapped within cages in the gelatin that are formed from the crosslinking. This dual measure allows for controlled and sustained release of the active agent from the hemostatic agent to reduce surgical site infections.


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