The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Jan. 28, 2020
Applicants:
University of Rhode Island Board of Trustees, Kingston, RI (US);
Yale University, New Haven, CT (US);
Inventors:
Yana K. Reshetnyak, Saunderstown, RI (US);
Oleg A. Andreev, Saunderstown, RI (US);
Donald M. Engelman, New Haven, CT (US);
Anna Moshnikova, Warwick, RI (US);
John Deacon, Tolland, CT (US);
Assignees:
University of Rhode Island Board of Trustees, Kingston, RI (US);
Yale University, New Haven, CT (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 9/00 (2006.01); A61K 39/39 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 47/64 (2017.08); A61K 9/0019 (2013.01); A61K 39/39 (2013.01); A61K 47/42 (2013.01);
Abstract
The invention features a composition comprising an immuno-stimulatory compound and a pHLIP® peptide, e.g., an immunostimulatory compound that comprises a cyclic purine dinucleotide, which binds to a stimulator of interferon genes (STING) such as a cGAMP cyclic compound inside a cell.