The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Dec. 23, 2020
Applicant:

Metagenics, Inc., Aliso Viejo, CA (US);

Inventors:

Annalouise O'connor, Gig Harbor, WA (US);

Mark Houston, Nashville, TN (US);

Assignee:

METAGENICS LLC, Aliso Viejo, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/185 (2006.01); A61K 31/01 (2006.01); A61K 31/05 (2006.01); A61K 31/352 (2006.01); A61P 3/06 (2006.01);
U.S. Cl.
CPC ...
A61K 36/185 (2013.01); A61K 31/01 (2013.01); A61K 31/05 (2013.01); A61K 31/352 (2013.01); A61P 3/06 (2018.01);
Abstract

This disclosure provides a composition and a method for enhancing urolithin B production. As a result of this, due to known impact of urolithin B, this can enhance reverse cholesterol transport and HDL function and management of plasma lipid profile through enhanced production of urolithin B from pomegranate polyphenols by administering a composition comprising a synergistic mixture of pomegranate polyphenols, lycopene and quercetin. The improved HDL function and lipid profile of such composition may be attributed to the enhanced urolithin B production made possible by the combination. Increasing the levels of urolithin B through modulation of the intestinal microbiome metabolism of pomegranate polyphenols is a potential therapeutic target for managing these diseases.


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