The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Jan. 07, 2020
Applicant:
Intra-cellular Therapies, Inc., New York, NY (US);
Inventors:
Gretchen Snyder, New York, NY (US);
Lawrence P. Wennogle, Hillsborough, NJ (US);
Jennifer O'brien, New York, NY (US);
Joseph Hendrick, New York, NY (US);
Robert Davis, San Diego, CA (US);
Assignee:
INTRA-CELLULAR THERAPIES, INC., Bedminster, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61P 35/00 (2018.01);
Abstract
The disclosure relates to the use of phosphodiesterase 1 (PDE1) inhibitors for the treatment of cancers and tumors, including for inhibiting tumor recruitment of macrophages and other cells to the tumor or cancer, for complementing and enhancing checkpoint inhibitor therapies, and for mitigating the side effects (i.e., inflammatory-related adverse events) associated with checkpoint inhibitor therapies.