The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Oct. 26, 2022
Applicants:

Krunal Raval, Ahmedabad, IN;

Suresh Borsadia, Plainsboro, NJ (US);

Kalpana Patel, West Windsor, NJ (US);

Gurpartap Singh Sachdeva, Princeton Junction, NJ (US);

Inventors:

Krunal Raval, Ahmedabad, IN;

Suresh Borsadia, Plainsboro, NJ (US);

Kalpana Patel, West Windsor, NJ (US);

Gurpartap Singh Sachdeva, Princeton Junction, NJ (US);

Assignee:

Shinkei Therapeutics, Inc., Princeton, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/13 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/13 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 47/02 (2013.01);
Abstract

The invention is a dosing regimen for administering an aqueous composition of amantadine hydrochloride to a patient having a traumatic brain injury. The dosing regimen includes administering a first dose and a second dose of amantadine hydrochloride by intravenous injection. The first dose comprises between 100-200 mg of amantadine hydrochloride in an aqueous solution of about 200-300 ml over a period of about two to about four hours. The second dose comprises between 100-200 mg of amantadine hydrochloride in an aqueous solution of about 200-300 ml over a period of about two to about four hours. The second dose is administered after about four to six hours after the first dose is fully administered.


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