The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Aug. 12, 2020
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
Kerry E. Benenato, Sudbury, MA (US);
William Butcher, Winthrop, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 38/18 (2006.01); A61K 47/22 (2006.01); A61K 48/00 (2006.01); C07D 211/14 (2006.01); C07D 211/16 (2006.01); C07D 241/04 (2006.01); C07D 295/13 (2006.01); C07D 295/185 (2006.01); A61K 9/127 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 38/1808 (2013.01); A61K 38/1816 (2013.01); A61K 47/22 (2013.01); A61K 48/0058 (2013.01); C07D 211/14 (2013.01); C07D 211/16 (2013.01); C07D 241/04 (2013.01); C07D 295/13 (2013.01); C07D 295/185 (2013.01); A61K 9/127 (2013.01); B82Y 5/00 (2013.01);
Abstract
The disclosure features amino lipids and compositions involving the same. Nanoparticle compositions include an amino lipid as well as additional lipids such as phospholipids, structural lipids, PEG lipids, or a combination thereof. Nanoparticle compositions further including therapeutic and/or prophylactic agents such as RNA are useful in the delivery of therapeutic and/or prophylactic agents to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.