The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
May. 31, 2024
Applicant:
Lonza Walkersville, Inc., Walkersville, MD (US);
Inventors:
Assignee:
LONZA WALKERSVILLE, INC., Walkersville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/867 (2006.01); C07K 14/16 (2006.01); C12N 5/071 (2010.01); C12N 9/12 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 15/867 (2013.01); C07K 14/161 (2013.01); C07K 14/162 (2013.01); C07K 14/163 (2013.01); C12N 5/0686 (2013.01); C12N 9/1241 (2013.01); C12N 15/8673 (2013.01); C12N 15/8676 (2013.01); C12N 15/86 (2013.01); C12N 2740/15051 (2013.01); C12N 2740/16052 (2013.01); C12N 2760/20222 (2013.01);
Abstract
The present disclosure relates to methods for producing lentiviral vector-producing cells. Specifically the methods utilize two plasmids, rather than four, to provide the required packaging elements and transfer vector to a cell, allowing for the production of a large number of lentiviral producer cells, including suspension-based cells, and the production of high amounts of lentivirus. These methods allow for the production of cells that can be later induced to produce lentivirus, and can be tailored to include a specific gene of interest.