The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2025

Filed:

Dec. 05, 2023
Applicant:

Northeast Agricultural University, Heilongjiang, CN;

Inventors:

Bailiang Li, Heilongjiang, CN;

Zhongjiang Wang, Heilongjiang, CN;

Zengbo Wang, Heilongjiang, CN;

Zengwang Guo, Heilongjiang, CN;

Qingxue Chen, Heilongjiang, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); A61K 35/00 (2006.01); A61K 35/741 (2015.01); A61P 19/06 (2006.01); C12R 1/01 (2006.01);
U.S. Cl.
CPC ...
C12N 1/205 (2021.05); A61K 35/741 (2013.01); A61P 19/06 (2018.01); A61K 2035/115 (2013.01); C12R 2001/01 (2021.05);
Abstract

The present disclosure provides astrain for alleviating hyperuricemia and a combination and use thereof, and belongs to the technical field of microorganisms. Thestrain was deposited in the China Center for Type Culture Collection (CCTCC), Wuhan, China on Oct. 19, 2022, with an accession number of CCTCC NO: M20221596. The combination includes thestrain BL-17, 0.01 wt % of a galacto-oligosaccharide, 0.01 wt % of an adenylic acid, and the balance of a sterilized skimmed milk solution. The combination according to the present disclosure can effectively alleviate the high serum uric acid levels in hyperuricemic rats, increase the urine uric acid levels in hyperuricemic rats, reduce the serum creatinine levels in hyperuricemic rats, reduce the serum urea nitrogen levels in hyperuricemic rats, and inhibit the activity of xanthine oxidase (XOD) in the serum and liver of hyperuricemic rats, and has an effect for alleviating hyperuricemia.


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