The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Aug. 11, 2022
Applicant:
Flaskworks, Llc, Boston, MA (US);
Inventors:
Shashi K. Murthy, Newton, MA (US);
Andrew Kozbial, East Boston, MA (US);
Assignee:
FLASKWORKS, LLC, Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); A01N 1/125 (2025.01); A61K 35/17 (2015.01); C12M 1/04 (2006.01); C12M 1/12 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01); C12M 1/36 (2006.01); C12M 1/42 (2006.01); C12M 3/00 (2006.01); C12N 5/00 (2006.01); C12N 5/0783 (2010.01); C12N 5/0784 (2010.01);
U.S. Cl.
CPC ...
C12M 23/58 (2013.01); A01N 1/125 (2025.01); A61K 35/17 (2013.01); C12M 23/24 (2013.01); C12M 23/48 (2013.01); C12M 29/00 (2013.01); C12M 29/10 (2013.01); C12M 29/14 (2013.01); C12M 33/12 (2013.01); C12M 35/08 (2013.01); C12M 37/04 (2013.01); C12M 41/14 (2013.01); C12M 41/34 (2013.01); C12M 41/48 (2013.01); C12M 45/22 (2013.01); C12N 5/00 (2013.01); C12N 5/0636 (2013.01); C12N 5/0637 (2013.01); C12N 5/0638 (2013.01); C12N 5/0639 (2013.01); C12N 2501/998 (2013.01); C12N 2502/1121 (2013.01); C12N 2502/1157 (2013.01);
Abstract
Cell culture systems and methods provide improved immunotherapeutic product manufacturing with greater scalability, flexibility, and automation. Cell culture systems are configured with interchangeable cartridges, allowing versatility and scalability. Systems are configured to have multiple connected cell culture chambers, which allows parallel processing of different types of cells. Gas-impermeable cell culture chambers and methods for generating cells in closed systems prevent contamination and user error. Methods for recycling cell culture medium provide additional efficiencies.