The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Aug. 20, 2019
Applicants:
1globe Biomedical Co., Ltd., Beijing, CN;
1globe Health Institute Llc, Norwood, MA (US);
Inventors:
Chiang J. Li, Cambridge, MA (US);
Shyam Unniraman, Newton, MA (US);
Hannah Bader, Waltham, MA (US);
Mithilesh Jha, Sharon, MA (US);
Assignees:
1GLOBE BIOMEDICAL CO., LTD., Beijing, CN;
1GLOBE HEALTH INSTITUTE LLC, Norwood, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 45/06 (2013.01); C07K 2317/21 (2013.01); C07K 2317/52 (2013.01); C07K 2317/56 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
Provided are compositions and methods relating to or derived from anti-PD-L1 antibodies with ADCC and/or CDC activities. More specifically, provided are fully human antibodies that bind PD-L1, PD-L1-binding antibody fragments, derivatives of such antibodies, and PD-L1-binding polypeptides comprising such fragments.