The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
May. 23, 2023
Applicant:
Gyros Protein Technologies Ab, Uppsala, SE;
Inventors:
Robert Zitterbart, Berlin, DE;
Oliver Reimann, Berlin, DE;
Assignee:
GYROS PROTEIN TECHNOLOGIES AB, Uppsala, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); C07C 247/18 (2006.01); C07D 213/75 (2006.01); C07D 295/185 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); C07C 247/18 (2013.01); C07D 213/75 (2013.01); C07D 295/185 (2013.01);
Abstract
The present invention relates to linker molecules of formula (1), X-T-V—U—Y—Z (1) and a method for purifying peptides using said linker molecules. The linker molecule can be coupled to a purification resin via the moiety X and to a peptide via the moiety Y under the release of the leaving group Z. T is an optional spacer moiety and V is an optional electron withdrawing moiety. U is an aryl or 5- or 6-membered heteroaryl moiety bound to at least one electron withdrawing moiety V, W or E. The linker is stable under acidic conditions and releases the peptide upon addition of a reducing agent.