The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Feb. 02, 2021
Shenzhen Neptunus Pharmaceutical Research Institute Co., Ltd., Shenzhen, CN;
Shenglin Luan, Shenzhen, CN;
Tian Tang, Shenzhen, CN;
Hanmin Huang, Shenzhen, CN;
Jing Wu, Shenzhen, CN;
Yidong Feng, Shenzhen, CN;
Tao Shi, Shenzhen, CN;
Hanlin Feng, Shenzhen, CN;
Lin Yu, Shenzhen, CN;
Abstract
The present invention relates to a multi-target tyrosine kinase inhibitor, which is a compound having protein kinase inhibitory activity as shown in formula (I). The compound is metabolized into an active small molecule td32-4 that inhibits tumor growth in vivo, so as to achieve the anti-tumor effect. Compared with td32-4, the compound of the present invention has significantly improved solubility and oral bioavailability, and shows strong anti-tumor activity in animal in vivo experiments. The present invention relates to a synthetic method for the compound of formula (I) and an application thereof in the field of pharmaceuticals.