The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Mar. 08, 2022
Applicant:
Amgen Inc., Thousand Oaks, CA (US);
Inventors:
Andrew Thomas Parsons, Cambridge, MA (US);
Brian Mcneil Cochran, San Diego, CA (US);
William Powazinik, Iv, Thousand Oaks, CA (US);
Marc Anthony Caporini, Belmont, MA (US);
Assignee:
AMGEN INC., Thousand Oaks, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/235 (2006.01); A61K 31/341 (2006.01); A61K 31/4985 (2006.01); C07C 69/76 (2006.01); C07C 309/24 (2006.01); C07D 307/06 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07C 69/76 (2013.01); C07C 309/24 (2013.01);
Abstract
The present invention relates to an improved, efficient, scalable process to prepare intermediate compounds, such as compound 5M, having the structure useful for the synthesis of compounds that target KRAS G12C mutations, such as