The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Aug. 20, 2019
Applicants:
The Broad Institute, Inc., Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Amit Choudhary, Boston, MA (US);
Basudeb Maji, Cambridge, MA (US);
Soumyashree Ashok Gangopadhyay, Boston, MA (US);
Miseon Lee, Cambridge, MA (US);
Mengchao Shi, Boston, MA (US);
Assignees:
The Broad Institute, Inc., Cambridge, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/4745 (2006.01); A61K 31/7105 (2006.01); A61K 38/46 (2006.01); A61K 47/54 (2017.01); C12N 9/99 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4745 (2013.01); A61K 31/7105 (2013.01); A61K 38/465 (2013.01); A61K 47/54 (2017.08); A61K 47/545 (2017.08); C12N 9/99 (2013.01);
Abstract
Compositions and methods for inhibiting the activity of RNA-guided endonucleases, and methods for identifying such compositions are included. Methods of treatment using the inhibitory compounds, formulations and methods are also detailed, as well as control of nucleic acid editing systems and methods using said compounds.