The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2025

Filed:

Jan. 16, 2020
Applicants:

Fondazione Istituto Italiano Di Tecnologia, Genoa, IT;

Istituto Giannina Gaslini, Genoa, IT;

Fondazione Per LA Ricerca Sulla Fibrosi Cistica—onlus, Verona, IT;

Inventors:

Tiziano Bandiera, Genoa, IT;

Fabio Bertozzi, Genoa, IT;

Giorgia Zaetta, Genoa, IT;

Frederico Sorana, Verona, IT;

Emanuela Caci, Verona, IT;

Loretta Ferrera, Verona, IT;

Nicoletta Pedemonte, Genoa, IT;

Luis Juan Vicente Galietta, Genoa, IT;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 413/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); C07D 413/04 (2013.01);
Abstract

The present invention relates to compounds of Formula (Ia) or pharmaceutically acceptable salts, hydrates, solvates, clathrates, polymorphs, stereoisomers thereof. It further discloses a pharmaceutical composition comprising compounds of Formula (Ia) and the use of compounds of Formula (Ib), in particular to modulate CFTR protein or ABC protein activities.


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