The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Oct. 11, 2019
Applicant:
Inventisbio Co., Ltd., Shanghai, CN;
Inventors:
Xing Dai, Shanghai, CN;
Yaolin Wang, Shanghai, CN;
Yueheng Jiang, Shanghai, CN;
Yanqin Liu, Shanghai, CN;
Zixing Han, Shanghai, CN;
Zhenwu Wang, Shanghai, CN;
Liangshan Tao, Shanghai, CN;
Zhe Shi, Shanghai, CN;
Assignee:
INVENTISBIO CO., LTD., Shanghai, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/501 (2006.01); A61K 31/53 (2006.01); A61P 5/16 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07F 9/6509 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/501 (2013.01); A61K 31/53 (2013.01); A61P 5/16 (2018.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07F 9/650905 (2013.01);
Abstract
Provided herein are novel thyroid hormone receptor (TR) agonists e.g., having Formula I, II, or III. Also provided are methods of preparing the novel TR agonists and method of using the novel TR agonists for treating diseases or disorder modulated by TR agonists, such as NAFLD, NASH, diabetes, hyperlipidemia and/or hypercholesterolemia.