The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Jan. 13, 2020
Applicant:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Inventors:
Ashvinikumar V. Gavai, Princeton Junction, NJ (US);
Derek J. Norris, Pennington, NJ (US);
Daniel O'malley, New Hope, PA (US);
Steven P. Seitz, Swarthmore, PA (US);
Jay A. Markwalder, Lahaska, PA (US);
David K. Williams, Delran, NJ (US);
Hua Gong, King of Prussia, PA (US);
Scott Hunter Watterson, Pennington, NJ (US);
Christine M. Tarby, Lawrenceville, NJ (US);
Assignee:
Innate Tumor Immunity, Inc., Princeton, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 487/10 (2006.01); C07D 491/08 (2006.01); C07D 493/08 (2006.01); C07D 493/10 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); A61P 35/00 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 487/10 (2013.01); C07D 491/08 (2013.01); C07D 493/08 (2013.01); C07D 493/10 (2013.01); C07D 498/08 (2013.01);
Abstract
The present invention provides compounds of Formula (I): (I) wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).