The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2025

Filed:

May. 31, 2024
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Alan S. Verkman, San Francisco, CA (US);

Marc H. Levin, San Francisco, CA (US);

Onur Cil, San Francisco, CA (US);

Sujin Lee, San Francisco, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 251/52 (2006.01); A61K 31/496 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); A61P 1/10 (2006.01); A61P 27/04 (2006.01); C07D 251/46 (2006.01); C07D 403/04 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 251/52 (2013.01); A61K 31/496 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); A61P 1/10 (2018.01); A61P 27/04 (2018.01); C07D 251/46 (2013.01); C07D 403/04 (2013.01); C07D 413/12 (2013.01);
Abstract

Provided herein are compounds that activate CFTR and methods for treating constipation, dry eye disorders, and other diseases and disorders.


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