The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Jul. 12, 2023
Applicant:
Nikang Therapeutics, Inc., Wilmington, DE (US);
Assignee:
NiKang Therapeutics, Inc., Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 255/54 (2006.01); A61K 31/277 (2006.01); A61K 31/4412 (2006.01); A61K 45/06 (2006.01); A61P 1/16 (2006.01); A61P 9/12 (2006.01); A61P 11/00 (2006.01); A61P 35/00 (2006.01); C07C 49/747 (2006.01); C07C 225/20 (2006.01); C07C 255/50 (2006.01); C07C 311/07 (2006.01); C07C 313/06 (2006.01); C07D 213/63 (2006.01); C07D 213/65 (2006.01); C07D 233/60 (2006.01);
U.S. Cl.
CPC ...
C07C 255/54 (2013.01); A61P 35/00 (2018.01); C07C 313/06 (2013.01); C07D 213/63 (2013.01); C07D 233/60 (2013.01); A61K 45/06 (2013.01); C07C 2603/10 (2017.05); C07C 2603/97 (2017.05);
Abstract
The present disclosure provides certain tetrahydro-1H-cyclopenta[cd]indene compounds that are Hypoxia Inducible Factor 2α (HIF-2α) inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of HIF-2α. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.