The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Jan. 12, 2022
Definitive Biotechnologies Llc, Elkridge, MD (US);
Timothy Alcorn, Raleigh, NC (US);
Steven Dietl, Raleigh, NY (US);
Robert Altavela, Webster, NY (US);
Michael Carlotta, Lilburn, GA (US);
John C. Detter, Melbourne Beach, FL (US);
Todd Haran, Bloomfield, NY (US);
Michael Murray, Bloomfield, NY (US);
Scott Rosebrough, Avon, NY (US);
Jeffrey Serbicki, Holley, NY (US);
DEFINITIVE BIOTECHNOLOGIES LLC, Elkridge, MD (US);
Abstract
A device for amplifying and detecting nucleic acids in a biological sample has a sample port for receiving a biological sample, a solid-state membrane, a sample conduit, a lysis station, a wash station, an elution station, a waste chamber, and a reaction chamber. The sample port, lysis station and sample conduit are configured to mix a sample and lysis agent to form a sample-lysis mixture, pass the mixture across the solid-state membrane to capture nucleic acids in the sample therein, and receive the remainder of the mixture in the waste chamber. The wash station directs a wash solution across the solid-state membrane and into the waste chamber to purify nucleic acids captured in the membrane. The elution station directs an eluent across the membrane, elutes captured nucleic acids from the membrane, and passes the captured nucleic acids into the reaction chamber for amplifying and detecting the captured nucleic acids.