The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Feb. 10, 2023
Sunnybrook Research Institute, Toronto, CA;
Vitreosonic Inc., Toronto, CA;
Gary Lloyd Ka Tao Yau, North York, CA;
Kullervo Henrik Hynynen, Toronto, CA;
VITREOSONIC INC., Toronto, CA;
SUNNYBROOK RESEARCH INSTITUTE, Toronto, CA;
Abstract
At ultrasound intensities below the cavitation threshold of the vitreous and blood cells (e.g., between 0.1 watts per square centimeter (W/cm) and 3.5 W/cm), relative hyperthermia can induce temperature elevations that result in hemolysis as well as liquefy vitreous, both of which can accelerate clearance. At high intensities (i.e., >800 W/cm2), with temperatures reaching >100 deg C., the target region may be vaporized. At intensities above the cavitation intensities short ultrasound bursts can result in mechanical fragmentation of the clot. In at least some examples, the present systems, devices and methods will allow for all of these modes of therapies.