The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Nov. 18, 2021
Applicant:
The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);
Inventors:
Hildegund C. J. Ertl, Villanova, PA (US);
Marcio O. Lasaro, Maple Shade, NJ (US);
Luis C. S. Ferreira, Sao Paulo, BR;
Assignee:
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY, Philadelphia, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/245 (2006.01); A61K 39/12 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); A61K 39/12 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/57 (2013.01); C07K 2319/00 (2013.01); C07K 2319/10 (2013.01); C12N 2710/10043 (2013.01); C12N 2710/16622 (2013.01); C12N 2710/16634 (2013.01); Y02A 50/30 (2018.01);
Abstract
Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided.