The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2025

Filed:

Feb. 05, 2021
Applicant:

Know Bio, Llc, Durham, NC (US);

Inventors:

Drew Folk, Durham, NC (US);

Ryan Gerald Anderson, Morrisville, NC (US);

John Kelly Simons, Cary, NC (US);

Mona Jasmine Rosales Ahonen, Durham, NC (US);

Rebecca Anthouard Mcdonald, Chapel Hill, NC (US);

Assignee:

KNOW BIO, LLC, Durham, NC (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/655 (2006.01); A01N 33/12 (2006.01); A01N 51/00 (2006.01); A01N 59/06 (2006.01); A01P 1/00 (2006.01); A61K 33/02 (2006.01); A61K 33/06 (2006.01); A61K 33/24 (2019.01); A61K 39/42 (2006.01); A61K 45/06 (2006.01); A61P 31/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/655 (2013.01); A01N 33/12 (2013.01); A01N 51/00 (2013.01); A01N 59/06 (2013.01); A01P 1/00 (2021.08); A61K 33/02 (2013.01); A61K 33/06 (2013.01); A61K 33/24 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); A61P 31/00 (2018.01);
Abstract

Several embodiments of NO releasing compounds are disclosed. In some embodiments, the structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and use of these structures. The compounds may be tailored to release nitric oxide in a controlled manner and can be useful, for example, for treating or preventing microbial infections, or reducing the microbial load of a microbial infection.


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