The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2025

Filed:

Jul. 11, 2023
Applicants:

Prizm, Llc, Chandler, AZ (US);

The University of Miami, Coral Gables, FL (US);

The University of Chicago, Chicago, IL (US);

Inventors:

Samuel Refetoff, Chicago, IL (US);

Roy Weiss, Miami Beach, FL (US);

Khemraj Hirani, Chandler, AZ (US);

Assignees:

PriZm, LLC, Chandler, AZ (US);

The University of Miami, Coral Gables, FL (US);

The University of Chicago, Chicago, IL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61P 5/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61P 5/16 (2018.01);
Abstract

The present subject matter is directed to methods of treating Allan-Herndon-Dudley syndrome comprising administering 3,5-diiodothyropropionic acid (DITPA) to a subject in need thereof, wherein the DITPA administration reduces triiodothyronine ('T3') serum levels to normal, increases T3 brain levels to normal, and maintains normal serum levels of thyroxine (T4) and thyroid stimulating hormone (TSH). The subject may be a child or an adult.


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