The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2025
Filed:
Sep. 10, 2021
Applicant:
The Scripps Research Institute, La Jolla, CA (US);
Inventors:
Jiajia Dong, Shanghai, CN;
K. Barry Sharpless, La Jolla, CA (US);
Jeffery W. Kelly, La Jolla, CA (US);
Aleksandra Baranczak, Gurnee, IL (US);
Wentao Chen, Walnut Creek, CA (US);
Assignee:
THE SCRIPPS RESEARCH INSTITUTE, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/02 (2006.01); A61K 31/05 (2006.01); A61K 31/136 (2006.01); A61K 31/14 (2006.01); A61K 31/197 (2006.01); A61K 31/198 (2006.01); A61K 31/397 (2006.01); A61K 31/40 (2006.01); A61K 31/4045 (2006.01); A61K 31/407 (2006.01); A61K 31/4168 (2006.01); A61K 31/4245 (2006.01); A61K 31/4353 (2006.01); A61K 31/439 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); A61K 31/473 (2006.01); A61K 31/4745 (2006.01); A61K 31/485 (2006.01); A61K 31/505 (2006.01); A61K 31/515 (2006.01); A61K 31/53 (2006.01); A61K 31/5513 (2006.01); A61K 31/56 (2006.01); A61K 31/65 (2006.01); A61K 31/655 (2006.01); A61K 31/70 (2006.01); A61K 31/7048 (2006.01); A61K 38/31 (2006.01); A61K 47/54 (2017.01); A61K 51/04 (2006.01); C07C 305/26 (2006.01); C07D 277/82 (2006.01); C07D 279/08 (2006.01); C07D 295/088 (2006.01); C07D 295/185 (2006.01); C07D 295/26 (2006.01); C07D 501/18 (2006.01); C07K 1/113 (2006.01); C07K 2/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/05 (2013.01); A61K 31/136 (2013.01); A61K 31/14 (2013.01); A61K 31/197 (2013.01); A61K 31/198 (2013.01); A61K 31/397 (2013.01); A61K 31/40 (2013.01); A61K 31/4045 (2013.01); A61K 31/407 (2013.01); A61K 31/4168 (2013.01); A61K 31/4245 (2013.01); A61K 31/4353 (2013.01); A61K 31/439 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); A61K 31/473 (2013.01); A61K 31/4745 (2013.01); A61K 31/485 (2013.01); A61K 31/505 (2013.01); A61K 31/515 (2013.01); A61K 31/53 (2013.01); A61K 31/5513 (2013.01); A61K 31/56 (2013.01); A61K 31/65 (2013.01); A61K 31/655 (2013.01); A61K 31/70 (2013.01); A61K 31/7048 (2013.01); A61K 38/31 (2013.01); A61K 47/54 (2017.08); A61K 51/0497 (2013.01); C07C 305/26 (2013.01); C07D 277/82 (2013.01); C07D 279/08 (2013.01); C07D 295/088 (2013.01); C07D 295/185 (2013.01); C07D 295/26 (2013.01); C07D 501/18 (2013.01); C07K 1/02 (2013.01); C07K 1/1136 (2013.01); C07K 2/00 (2013.01); C07C 2601/14 (2017.05); C07C 2603/18 (2017.05);
Abstract
This application describes modified amino acids and polypeptides comprising a SOF or CHCHSOF group bound to the side chain of an amino acid or amino acid residue of a polypeptide in place of a hydrogen of a hydroxyl or amino substituent thereof. Methods of covalently binding the polypeptides to receptor sites of receptor proteins are also described herein.