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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12385926 B1

PDFFull Text
Date of Patent:
Aug. 12, 2025

Filed:

May. 31, 2018

Mmp-8 as a marker for identifying infectious disease

Applicants:

B.r.a.h.m.s Gmbh, Hennigsdorf, DE;

Fundacion Instituto DE Estudios DE Ciencias DE LA Salud DE Castilla Y Leon, Soria, ES;

Inventors:

Jesus F. Bermejo Martin, Soria, ES;

Eduardo Tamayo Gomez, Soria, ES;

David Andaluz Ojeda, Soria, ES;

Lydia Blanco Peris, Soria, ES;

Alicia Ortega Andres, Soria, ES;

Raquel Almansa Mora, Soria, ES;

Assignees:

B.R.A.H.M.S GmbH, Hennigsdorf, DE;

Fundacion Instituto de Estudios de Ciencias de la Salud de Castilla y Leon, Soria, ES;

Attorney:

Ryan Pool

Primary Examiner:

Misook Yu

Assistant Examiner:

Marianne Dibrino

Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); A61K 31/43 (2006.01); A61K 31/431 (2006.01); A61K 31/7048 (2006.01); A61K 35/00 (2006.01); A61K 36/00 (2006.01); G01N 33/68 (2006.01); C07G 11/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6893 (2013.01); C12Q 1/6883 (2013.01); G01N 2333/988 (2013.01); G01N 2800/102 (2013.01); G01N 2800/26 (2013.01); G01N 2800/50 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention relates to a method for the diagnosis, prognosis, risk assessment, risk stratification, monitoring, therapy guidance and/or therapy control of an infectious disease in a subject, wherein said method comprises providing a sample of said subject; determining a level of matrix metalloprotease-8 (MMP-8) or fragment(s) thereof in a sample of said subject, wherein said level of MMP-8 or fragment(s) thereof distinguishes between the presence and absence of an infectious disease in a patient with symptoms of a systemic inflammatory condition. In a preferred embodiment the invention relates to the determination of procalcitonin (PCT) and MMP-8 and their combined use to distinguish between the presence and absence of infectious disease in patients with symptoms of systemic inflammatory condition. The invention also relates to a computer-implemented method and a kit for conducting the method of the invention.

Find Patent Forward Citations

Bermejo Martin, Jesus. (2025). Mmp-8 as a marker for identifying infectious disease (U.S. Patent No. 12385926). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12385926

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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