The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2025

Filed:

Jan. 11, 2023
Applicant:

Adagene Inc., Grand Cayman, KY;

Inventors:

Peter Peizhi Luo, Lansdale, PA (US);

Yan Li, Jiangsu, CN;

Fangyong Du, Jiangsu, CN;

Assignee:

Adagene Inc., Grand Cayman, KY;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/08 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
C40B 40/08 (2013.01); C07K 16/00 (2013.01); C07K 2317/51 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01);
Abstract

Provided herein are libraries containing polynucleotides, where one of the polynucleotides encodes an antibody heavy chain with specific hypervariable regions HVR-H1 and HVR-H2. Further provided herein are libraries containing polynucleotides encoding a plurality of unique antibodies, wherein each antibody comprises a heavy chain variable region and a light chain variable region. Also provided are antibodies, polypeptide libraries, vector libraries, cells, non-human animals, antibody heavy chains, methods of making an antibody library, kits, and methods of generating a bispecific antibody related thereto.


Find Patent Forward Citations

Luo, Peter. (2025). Dynamic human heavy chain antibody libraries (U.S. Patent No. 12385162). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12385162

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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