The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Nov. 18, 2021
Applicant:
Guardant Health, Inc., Redwood City, CA (US);
Inventor:
Darya Chudova, San Jose, CA (US);
Assignee:
Guardant Health, Inc., Palo Alto, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/6886 (2018.01); G16B 20/00 (2019.01); G16B 20/20 (2019.01); G16H 50/30 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); G16B 20/00 (2019.02); G16B 20/20 (2019.02); G16H 50/30 (2018.01); C12Q 2600/112 (2013.01); C12Q 2600/156 (2013.01);
Abstract
Values for tumor mutation burden from different samples can be made more comparable to each other or control standards by a normalization regime that takes into account the minor allele fraction of highly rated mutations in a sample. Such analysis can provide an indication where the tumor mutation burden of a test sample lies on a distribution of tumor mutation burdens in a control population, and thus, whether the individual providing the test sample is likely to be amenable to immunotherapy to treat cancer.