The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2025

Filed:

Nov. 02, 2023
Applicants:

Illumina Cambridge Limited, Cambridge, GB;

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Niall Anthony Gormley, Cambridge, GB;

Andreas Gnirke, Cambridge, MA (US);

David Jaffe, Cambridge, MA (US);

Harris Nusbaum, Cambridge, MA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6855 (2018.01); C12Q 1/6809 (2018.01); C12Q 1/6827 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6855 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6827 (2013.01);
Abstract

The invention relates to a method of preparing and using a library of template polynucleotides suitable for use as templates in solid-phase nucleic acid amplification and sequencing reactions to determine the methylation status of the cytosine bases in the library. In particular, the invention relates to a method of preparing and analysing a library of template polynucleotides suitable for methylation analysis.


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