The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Jun. 23, 2022
Applicant:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Inventors:
Michael Torrens-Spence, Cambridge, MA (US);
Jing-Ke Weng, Belmont, MA (US);
Assignee:
Whitehead Institute for Biomedical Research, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12N 15/70 (2006.01); C12N 15/74 (2006.01); C12N 15/81 (2006.01); C12N 15/82 (2006.01); C12P 17/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8257 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12N 15/743 (2013.01); C12N 15/81 (2013.01); C12N 15/8243 (2013.01); C12N 15/8245 (2013.01); C12P 17/06 (2013.01); C12Y 114/13068 (2013.01); C12Y 204/0117 (2013.01); C12Y 401/01 (2013.01);
Abstract
Transgenic host cells, vectors useful for making transgenic host cells, and kits useful for making transgenic host cells are described. Also described are transgenic plants. In some embodiments, transgenic host cells express a 4-hydroxyphenylacetaldehyde synthase (4HPAAS). In some embodiments, transgenic host cells express a tyrosol:UDP-glucose 8-O-glucosyltransferase (T8GT). The transgenic host cells are useful for biosynthesis of one or more of salidroside, icariside D2, tyrosol, and 4-hydroxypenylacetaldehyde.