The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2025

Filed:

Mar. 21, 2023
Applicant:

Duke University, Durham, NC (US);

Inventors:

Michael Lynch, Durham, NC (US);

Jeovanna Rios, Durham, NC (US);

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/20 (2006.01); C07K 14/245 (2006.01); C12N 9/88 (2006.01); C12N 15/113 (2010.01); C12N 15/52 (2006.01); C12N 15/70 (2006.01); C12P 7/46 (2006.01); C12R 1/19 (2006.01);
U.S. Cl.
CPC ...
C12N 1/205 (2021.05); C12N 9/88 (2013.01); C12N 15/113 (2013.01); C12N 15/52 (2013.01); C12R 2001/19 (2021.05); C12Y 401/01009 (2013.01);
Abstract

Methods and microorganisms for improved malonyl-CoA flux and production of products having malonyl-CoA as a precursor. The methods comprise dynamically regulating, in a stationary phase of a method, a nitrogen regulatory protein. The methods may dynamically regulate more than one gene.


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