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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12384846 B1

PDFFull Text
Date of Patent:
Aug. 12, 2025

Filed:

Jul. 07, 2022

Targeting pd-l1 on tumor cells

Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Stephen James Russell, Rochester, MN (US);

Autumn J. Schulze, Rochester, MN (US);

Arun Ammayappan, Rochester, MN (US);

Kah-Whye Peng, Rochester, MN (US);

Camilo Ayala Breton, Rochester, MN (US);

Assignee:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Celine X Qian

Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/32 (2025.01); A61K 40/42 (2025.01); A61P 35/00 (2006.01); C07K 14/005 (2006.01); C07K 16/28 (2006.01); C12N 15/85 (2006.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2827 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/32 (2025.01); A61K 40/421 (2025.01); A61P 35/00 (2018.01); C07K 14/005 (2013.01); C07K 16/2809 (2013.01); C07K 16/2896 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); A61K 48/00 (2013.01); C07K 16/2818 (2013.01); C07K 2317/31 (2013.01); C07K 2317/622 (2013.01); C07K 2319/02 (2013.01); C07K 2319/33 (2013.01); C12N 15/00 (2013.01); C12N 2710/10343 (2013.01); C12N 2760/18422 (2013.01); C12N 2760/18423 (2013.01); C12N 2760/18433 (2013.01); C12N 2760/20243 (2013.01);
Abstract

This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.

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Quick Actions:

Russell, Stephen. (2025). Targeting pd-l1 on tumor cells (U.S. Patent No. 12384846). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12384846

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