The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
May. 18, 2023
Applicant:
Universitat Zurich, Zurich, CH;
Inventors:
Burkhard Becher, Maur, CH;
Sonia Tugues, Zurich, CH;
Assignee:
UNIVERSITAT ZURICH, Zurich, CH;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61P 35/02 (2006.01); A61P 37/06 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/243 (2013.01); A61P 35/02 (2018.01); A61P 37/06 (2018.01); C07K 16/2866 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01);
Abstract
Described herein is the use of a non-agonist ligand, particularly an antibody, specifically binding to GM-CSF or one of CD116, CD131 and the GM-CSF receptor composed of CD116 and CD131 for use in treatment of leukemia in a patient having undergone allo-HCT or in treatment of other complications arising as a consequence of hematopoietic cell transplantation from an immunologically non-identical donor.