The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2025

Filed:

Feb. 10, 2020
Applicant:

Ptc Therapeutics, Inc., Warren, NJ (US);

Inventors:

Nanjing Zhang, Princeton, NJ (US);

Michael A. Arnold, Flemington, NJ (US);

Amal Dakka, Whitehouse Station, NJ (US);

Gary Mitchell Karp, Princeton Junction, NJ (US);

Tom Tuan Luong, Cupertino, CA (US);

Jana Narasimhan, Scotch Plains, NJ (US);

Nikolai A. Naryshkin, East Brunswick, NJ (US);

Jiashi Wang, West New York, NJ (US);

Xiaoyan Zhang, Belle Mead, NJ (US);

Assignee:

PTC THERAPEUTICS, INC., Warren, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 25/00 (2018.01);
Abstract

The present description relates' to compounds of formula (I) useful for improving pre-mRNA splicing in a cell. In particular, another aspect of the present description relates to substituted thieno[3,2-b]pyridine compounds, forms, and pharmaceutical compositions thereof and methods of use for treating or ameliorating familial dysautonomia.


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