The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Aug. 10, 2023
Applicant:
Aclaris Therapeutics, Inc., Wayne, PA (US);
Inventors:
Gary A. Decrescenzo, Parkville, MO (US);
John Robert Springer, Wentzville, MO (US);
Assignee:
Aclaris Therapeutics, Inc., Wayne, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/12 (2013.01);
Abstract
The present disclosure provides methods of synthesizing a compound of Formula (P)-I. The method proceeds through several different pathways including several novel chiral separations, a Sonogashira coupling, a zinc mediated reductive cyanation, as well as through various halide containing intermediates. Also disclosed is the multi-kilogram preparation of several novel intermediates.
Quick Actions:
Decrescenzo, Gary. (2025). Methods of synthesizing substituted pyridinone-pyridinyl compounds (U.S. Patent No. 12384757). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12384757
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile