The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Oct. 16, 2019
Applicant:
William Marsh Rice University, Houston, TX (US);
Inventors:
Jeffrey Hartgerink, Houston, TX (US);
David Leach, Houston, TX (US);
Tania Lopez-Silva, Houston, TX (US);
Assignee:
William Marsh Rice University, Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A01N 1/128 (2025.01); A61L 27/22 (2006.01); A61L 27/52 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C12N 11/04 (2006.01);
U.S. Cl.
CPC ...
A61L 27/22 (2013.01); A01N 1/128 (2025.01); A61K 38/00 (2013.01); A61L 27/52 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C12N 11/04 (2013.01);
Abstract
Provided herein are peptide-based hydrogels, or neutral multidomain peptide hydrogel (NMDP), as well as uses thereof. The uses include encapsulating cells to induce quiescence for long-term storage and administering to a subject to induce collagen deposition and macrophage infiltration. The disclosed hydrogel is useful for the preservation of stem cells, including maintaining their quiescence and differentiation potential.