The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2025

Filed:

Jul. 24, 2019
Applicant:

Korea Basic Science Institute, Daejeon, KR;

Inventors:

Ki-Yuk Chang, Seoul, KR;

Kwan-Soo Hong, Cheongju-si, KR;

Chan-Woo Kim, Suwon-si, KR;

Hyeon-Seung Lee, Daejeon, KR;

Hyun-Min Kim, Gimje-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 49/0032 (2013.01); A61K 49/0058 (2013.01); C07K 16/28 (2013.01); G01N 33/57492 (2013.01); G01N 2333/70557 (2013.01);
Abstract

Disclosed are an αβintegrin targeting single-domain antibody and various applications thereof. The αβintegrin targeting single-domain antibody exhibits high binding ability to αβintegrin related to angiogenesis, excellent tissue permeability, and biostability compared to conventional antibodies. Further, the single-domain antibody may be combined with fluorescent particles and thus may be easily measured in vitro, in vivo or ex vivo, and may be effective in detecting angiogenesis and diagnosing angiogenesis related diseases, therefore it may be usefully used in related industries.


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