The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2025

Filed:

Apr. 19, 2018
Applicants:

Institute for Research IN Biomedicine, Bellinzona, CH;

Seattle Children's Hospital, Seattle, WA (US);

Schweizerisches Tropen—und Public Health-institut, Basel, CH;

Inventors:

Antonio Lanzavecchia, Porza, CH;

Joshua Hoong Yu Tan, Shah Alam, MY;

Claudia Daubenberger, Mülheim, DE;

Brandon Wilder, Seattle, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/015 (2006.01); A61K 39/00 (2006.01); A61P 33/06 (2006.01); C07K 16/20 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); A61P 33/06 (2018.01); C07K 16/205 (2013.01); A61K 2039/505 (2013.01);
Abstract

The present invention provides a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, for example for use in a malaria vaccine. The present invention also provides nucleic acids encoding a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1, compositions comprising a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1 and antibodies binding to a fragment of plasmodium circumsporozoite protein according to SEQ ID NO: 1. The antibodies according to the present invention bind specifically tosporozoites and may be used in the treatment and/or prevention of malaria.


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