The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2025
Filed:
Sep. 19, 2019
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
Örn Almarsson, Cambridge, MA (US);
Jin Lim, Lexington, MA (US);
Eugene Cheung, Sharon, MA (US);
Jaclyn Milton, Somerville, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 8/86 (2006.01); C08G 65/332 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5153 (2013.01); A61K 8/86 (2013.01); A61K 9/5123 (2013.01); C08G 65/3322 (2013.01);
Abstract
The present disclosure is based, at least in part, on the discovery that high-purity PEG lipids exhibit superior physical and biological properties, particularly when used in lipid nanoparticle (LNP) formulations. Therefore, the present disclosure provides PEG lipids at a recommended purity, e.g., for use in formulations, such as LNP formulations. The present disclosure also provides LNPs comprising the high-purity PEG lipids, and methods for delivering therapeutic agents to a subject using the same.