The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Feb. 17, 2021
Applicant:
Genentech, Inc., South San Francisco, CA (US);
Inventors:
Shan Chung, South San Francisco, CA (US);
Van Hong Nguyen, South San Francisco, CA (US);
An Song, South San Francisco, CA (US);
Assignee:
GENENTECH, INC., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); C07K 16/32 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5005 (2013.01); C07K 16/32 (2013.01); G01N 33/6854 (2013.01); C07K 2317/24 (2013.01); C07K 2317/526 (2013.01); C07K 2317/71 (2013.01); C07K 2317/72 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
The present disclosure relates to methods and compositions useful for measuring the transcytosis of a molecule. In particular, the present disclosure relates to in vitro receptor-dependent transcytosis assays for evaluating the clearance rates of therapeutic antibody molecules and Fc-fusion proteins in humans and animals.