The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2025
Filed:
Oct. 05, 2021
Applicant:
University of Iowa Research Foundation, Iowa City, IA (US);
Inventors:
James O. Mcnamara, Iowa City, IA (US);
Katie R. Flenker, Iowa City, IA (US);
Hyeon Kim, Iowa City, IA (US);
Alexander R. Horswill, Iowa City, IA (US);
Frank J. Hernandez, Iowa City, IA (US);
Mark Behlke, Coralville, IA (US);
Lingyan Huang, Coralville, IA (US);
Richard Owczarzy, Coralville, IA (US);
Elliot Burghardt, Iowa City, IA (US);
Karen Clark, Iowa City, IA (US);
Assignee:
UNIVERSITY OF IOWA RESEARCH FOUNDATION, Iowa City, IA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/689 (2018.01); A61K 49/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12Q 1/70 (2006.01); G01N 21/64 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); A61K 49/0054 (2013.01); C07H 21/02 (2013.01); C07H 21/04 (2013.01); C12Q 1/701 (2013.01); G01N 21/6428 (2013.01); G01N 33/581 (2013.01); G01N 2021/6432 (2013.01);
Abstract
The present invention relates to a rapid detection of microbial-associated nuclease activity with chemically modified nuclease (e.g., endonuclease) substrates, and probes and compositions useful in detection assays.